Cannabis Use Linked to 6 Times Higher Risk of Heart Attack in New Studies

Cannabis Use Linked to 6 Times Higher Risk of Heart Attack in New Studies

By Dr. Marcus Chen, Ph.D.

March 20, 2025 at 10:01 PM

Cannabis use appears to significantly increase heart attack risk, according to recent research. A major retrospective study found cannabis users under 50 were six times more likely to have a heart attack compared to non-users. Additionally, a meta-analysis of 12 studies with over 93,000 cannabis users showed a 50% higher heart attack risk.

Woman lighting marijuana cigarette

Woman lighting marijuana cigarette

Key findings from the retrospective study showed cannabis users had:

  • 6x higher risk of heart attack
  • 4x higher risk of ischemic stroke
  • 2x higher risk of heart failure
  • 3x higher risk of cardiovascular death, heart attack, or stroke

The study focused on participants under 50 who were otherwise healthy, with normal blood pressure and cholesterol levels, no diabetes, and no prior heart issues.

The meta-analysis examined 12 previous studies involving 4.5 million non-users and found heart attack risk peaked about one hour after cannabis use. However, researchers couldn't determine whether the risks differed between inhaled and ingested cannabis products.

Potential mechanisms for cardiovascular damage include:

  • Altered heart rhythm regulation
  • Increased oxygen demand on heart muscle
  • Blood vessel dysfunction
  • Impaired blood flow

Medical experts recommend that healthcare providers should assess cannabis use when evaluating cardiovascular risk, similar to tobacco use screening. While occasional, low-dose cannabis use may be relatively benign, the long-term effects remain unclear and require further research.

For those using cannabis, especially those with existing heart conditions or risk factors, it's important to:

  • Discuss cannabis use with healthcare providers
  • Be aware of potential cardiovascular risks
  • Monitor for any concerning symptoms
  • Stay informed about ongoing research

As cannabis legalization expands, more research is needed to fully understand its health impacts, particularly regarding different consumption methods and dosage levels. Until then, medical professionals advise caution, especially for those with existing cardiovascular risk factors.

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